1-Bromheptadecafluoroctan

Perfluorooctyl bromide

HCID 9873CAS 423-55-2

Grundinformationen

Standard-SMILES
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br
InChIKey
WTWWXOGTJWMJHI-UHFFFAOYSA-N
Summenformel
C8BrF17
Durchschnittliche Molmasse
498,96 g/mol
Monoisotopische Masse
497,89119

Namen und Bezeichner

Bevorzugter Name
Perfluorooctyl bromide
IUPAC
1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
Lokaler Name
1-Bromheptadecafluoroctan
Englischer Name
1-BroMoheptadecafluorooctane
Summenformel
C8BrF17
Molmasse
498.96

Namen und Synonyme

Perflubron423-55-21-BromoperfluorooctanePerfluorooctyl bromide1-BromoheptadecafluorooctanePerfluoroctyl bromide1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctanePerfluorooctylbromidePFOBN-perfluorooctyl bromideperfluorocaprylyl bromideDTXSID5046560
Weitere Namen anzeigen
ImagentHEPTADECAFLUORO-N-OCTYL BROMIDETBr-8uorooctanelong’scompound
OCTANE, 1-BROMOHEPTADECAFLUORO-Q1D0Q7R4D9Octane, 1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-DTXCID3026560CHEBI:38803perfluoroctylbromideperflubronumperfluorooctyliodide

Datenbank-Bezeichner

CAS
423-55-2
PubChem CID
9873
DTXSID
DTXSID5046560
ChEMBL
CHEMBL1200866
ChEBI
CHEBI:38803
UNII
Q1D0Q7R4D9
EC Number
207-028-4
Nikkaji
J94.754G

Eigenschaften

Berechnete Struktureigenschaften

XLogP
6,9
Polarare Oberfläche (TPSA)
0 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
17
Frei drehbare Bindungen
6
Schwere Atome
26

Experimentelle und physikochemische Eigenschaften

Kovats Retention Index581

Physikochemische Eigenschaften

Schmelzpunkt
6 °C · 6 °C
Siedepunkt
142 °C · 142 °C(lit.)
Dichte
1.93 g/mL · 1.93 g/mL at 25 °C(lit.)
Dampfdruck
12.8 · 12.8-72hPa at 25-65℃
Brechungsindex
20 · n20/D 1.305(lit.)
Flammpunkt
141 · 141-143°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Warning

H315 (90.9%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (90.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (89.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 55 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H413: May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

Gefahrenhinweise

Regulatory InformationStatus: Active Update: 22-10-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23055
Hazard Classes and Categories · 2 Einträge

Skin Irrit. 2 (90.9%);Eye Irrit. 2 (90.9%);STOT SE 3 (89.1%)

Hazardous to the aquatic environment (Long-term) - Category 4

Regulatorische Informationen

Regulatory InformationStatus: Active Update: 22-10-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23055

Sicherheitsdaten

wgk
3
ridadr
2810
hs_code
29037800
RTECS-Nr.
RG8700000
risk_code
36/37/38
Toxizität
LD50 i.v. in female rats: 41 g/kg (Burgan)

Chemie und Industrie

Pharmakologische Informationen

ATC Code · 2 Einträge

V - Various;V08 - Contrast media;V08C - Magnetic resonance imaging contrast media;V08CX - Other magnetic resonance imaging contrast media;V08CX01 - Perflubron

QV - Various;QV08 - Contrast media;QV08C - Magnetic resonance imaging contrast media;QV08CX - Other magnetic resonance imaging contrast media;QV08CX01 - Perflubron

Mechanism of Action · 1 Eintrag

Perflubron emulsion (Oxygent) maintains hemodynamic stability during major surgery, thereby potentially reducing or avoiding intraoperative transfusions of donor blood in major surgery.Perflubron emulsion has ability to enable patients to be physiologically stable and safe at lower intraoperative Hb levels.

MeSH Pharmacological Classification · 3 Einträge

Substances used to allow enhanced visualization of tissues.

Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells.

Agents that increase energy expenditure and weight loss by neural and metabolic regulation.

Verwendung und Herstellung

Uses · 2 Einträge

• Ophthalmology [Ref: https://doi.org/10.1155/2014/250323];• Oxygen carrier for artificial blood [Ref: https://doi.org/10.1039/c7gc03081a];• Solvent for printing ink [Ref: CAS2019 (CN109810567)];• X-ray imaging [Ref: https://doi.org/10.1007/978-1-4899-1202-2];• Supply of gases, including CO2, to microbial cells [Ref: https://doi.org/10.1007/978-1-4899-1202-2]

non-polymer PFAS -> Printing (Inks) -> Toner and printer inks;non-polymer PFAS -> Pharmaceutical Industry -> Processing aid in the manufacture of “microporous” particles;non-polymer PFAS -> Medicinal Utensils -> Retinal detachment surgery and proliferative vitreoretinopathy;non-polymer PFAS -> Medicinal Utensils -> Supplement conventional blood transfusion and artificial blood and perfusion of isolated organs;non-polymer PFAS -> Medicinal Utensils -> Contrast agent;non-polymer PFAS -> Biotechnology -> Supply of oxygen and other gases to cells in culture

Use ClassificationPFAS (per- and polyfluoroalkyl substances) -> OECD Category

Anwendungen

Verwenden1-BroMoheptadecafluorooctane can be used as oxygen carrier in emulsions used as blood substitutes.

Anbieter50 Anbieter

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