Propylene Glycol → Florfenicol Flunixin

HRID 1006517

Reaktionsgleichung

Reaktionsgleichung von HRID 1006517
C(O)C(O)C.[CH3:6][S:7]([C:10]1[CH:11]=[CH:12][C:13]([C@@H:16]([OH:26])[C@H:17]([NH:20][C:21]([CH:23]([Cl:25])[Cl:24])=[O:22])[CH2:18][F:19])=[CH:14][CH:15]=1)(=[O:9])=[O:8].[CH3:27][C:28]1[C:33]([NH:34][C:35]2[N:40]=[CH:39][CH:38]=[CH:37][C:36]=2[C:41]([OH:43])=[O:42])=[CH:32][CH:31]=[CH:30][C:29]=1[C:44]([F:47])([F:46])[F:45].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>CN1CCCC1=O>[CH3:6][S:7]([C:10]1[CH:11]=[CH:12][C:13]([C@@H:16]([OH:26])[C@H:17]([NH:20][C:21]([CH:23]([Cl:25])[Cl:24])=[O:22])[CH2:18][F:19])=[CH:14][CH:15]=1)(=[O:9])=[O:8].[CH3:27][C:28]1[C:33]([NH:34][C:35]2[N:40]=[CH:39][CH:38]=[CH:37][C:36]=2[C:41]([OH:43])=[O:42])=[CH:32][CH:31]=[CH:30][C:29]=1[C:44]([F:46])([F:45])[F:47]

Komponenten

5

Edukt 3

HCID 1030Propylene GlycolHCID 39212Flunixin MeglumineHCID 114811Florfenicol

Produkt 1

HCID 86602307Florfenicol Flunixin

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 13387N-methyl-2-pyrrolidoneLösungsmittel

Versuchsvorschrift

The N-methyl-2-pyrrolidone, propylene glycol and approximately 90% of the PEG 300 required were charged to the compounding vessel and mixed well. The florfenicol and flunixin meglumine were added with mixing until all solids were dissolved. The volume was adjusted with the remaining PEG 300.

Aufarbeitung

  1. additionmixed well
  2. additionwith mixing until all solids
  3. dissolutionwere dissolved

Quellen und Nachweise

ORD-Eintrag
ord-367a363c259c4279b1582a1a91f894dd
Quelldatensatz
uspto-grants-2004_09
Patentnummer
US06790867B2

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