HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(1-Pyrrolidinyl)piperidine → [5-Cyclopropyl-3-pyridin-4-yl-1-(3-trifluoromethoxy-phenyl)-1H-pyrazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(1-Pyrrolidinyl)piperidine | HCID 78703 | — |
| Edukt | 5-Cyclopropyl-3-pyridin-4-yl-1-(3-trifluoromethoxy-phenyl)-1H-pyrazole-4-carboxylic acid | HCID 67315604 | — |
| Produkt | [5-Cyclopropyl-3-pyridin-4-yl-1-(3-trifluoromethoxy-phenyl)-1H-pyrazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone | HCID 25206417 | 91% |
Reaktionsschritte
In analogy to the procedure described in Example 160E], 5-cyclopropyl-3-pyridin-4-yl-1-(3-trifluoromethoxy-phenyl)-1H-pyrazole-4-carboxylic acid and 4-(1-pyrrolidinyl)piperidine gave the title compound as a light yellow gum (91%). MS: 526.0 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07977358B2 |
| Quelldatensatz | uspto-grants-2011_07 |
| ORD ID | ord-34cf63468b20433baf2fae35dd84a51f |
| Quellennotiz | uspto-grants-2011_07 |