Sodium triacetoxyborohydride → 5-Bromo-1,2,3,4-tetrahydro-1-methylisoquinoline

HRID 1015056Notizen

Reaktionsgleichung

[Br:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]=[C:7]2[CH3:12].C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>>[Br:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][NH:6][CH:7]2[CH3:12]

Komponenten

Edukt 2

HCID 5049666Sodium triacetoxyborohydride

HCID 584164875-Bromo-1-methyl-3,4-dihydro-isoquinoline

Produkt 1

HCID 596625945-Bromo-1,2,3,4-tetrahydro-1-methylisoquinoline

Versuchsvorschrift

In close analogy to the procedure described above, 5-bromo-1-methyl-3,4-dihydro-isoquinoline is reacted with sodium triacetoxyborohydride to provide the title compound.

Quellen und Nachweise

ORD-Eintrag: ord-389ce2c408334c53ad9214890010879e
Quelldatensatz: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07985753B2

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