Sodium triacetoxyborohydride → 1-Methyl-5-methoxy-1,2,3,4-tetrahydro-isoquinoline

HRID 1015059

Reaktionsgleichung

[CH3:1][C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:4][N:3]=1.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>>[CH3:1][CH:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:4][NH:3]1

Komponenten

Edukt 2

HCID 5049666Sodium triacetoxyborohydride

HCID 450911955-Methoxy-1-methyl-3,4-dihydroisoquinoline

Produkt 1

HCID 183156461-Methyl-5-methoxy-1,2,3,4-tetrahydro-isoquinoline

Versuchsvorschrift

In close analogy to the procedure described above, 1-Methyl-5-methoxy-3,4-dihydro-isoquinoline is reacted with sodium triacetoxyborohydride to provide the title compound.

Quellen und Nachweise

ORD-Eintrag: ord-7c744e0078184181a171410382872698
Quelldatensatz: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07985753B2

Verknüpfte Notizen

Wird geladen…