2-Benzothiazolinone, hydrazone → HCID 14851333, Verbindung

HRID 1029467

Reaktionsgleichung

Reaktionsgleichung von HRID 1029467
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH2:9][C:10](=O)[CH:11]([CH3:13])[CH3:12])=[CH:4][CH:3]=1.[NH:16]([C:18]1[S:19][C:20]2[CH:26]=[CH:25][CH:24]=[CH:23][C:21]=2[N:22]=1)[NH2:17]>C(O)(=O)C>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:16]([C:18]3[S:19][C:20]4[CH:26]=[CH:25][CH:24]=[CH:23][C:21]=4[N:22]=3)[N:17]=[C:10]([CH:11]([CH3:13])[CH3:12])[CH:9]=2)=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 119882-Benzothiazolinone, hydrazoneHCID 141543761-(4-Fluorophenyl)-4-methylpentane-1,3-dione

Produkt 1

HCID 14851333HCID 14851333, VerbindungAusbeute 92,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

To a solution of the 1,3-diketone (103 g, 495 mmol) (preparation described in Example 1, Step A) in glacial acetic acid (800 mL) was added 2-hydrazinobenzothiazole (85.8 g, 520 mmol). The resulting solution was refluxed for 2.5 hours and then cooled to room temperature overnight. The resulting precipitate was collected, washed with water and dried overnight to give 154 g (92%) of a cream colored solid.

Aufarbeitung

  1. temperatureThe resulting solution was refluxed for 2.5 hours
  2. customThe resulting precipitate was collected
  3. washwashed with water
  4. customdried overnight

Quellen und Nachweise

ORD-Eintrag
ord-9fa8270522b34bd08b28b52938339b09
Quelldatensatz
uspto-grants-1992_04
Patentnummer
US05102893

Verknüpfte Notizen

Wird geladen…