Potassium Iodide → HCID 14556323, Verbindung

HRID 1032339Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1032339
Br[CH:2]([C:10]1[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=1)[C:3]1[CH:8]=[CH:7][C:6]([F:9])=[CH:5][CH:4]=1.[Br:17][CH2:18][CH2:19][CH2:20][OH:21].C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>O>[F:9][C:6]1[CH:7]=[CH:8][C:3]([CH:2]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)[O:21][CH2:20][CH2:19][CH2:18][Br:17])=[CH:4][CH:5]=1

Komponenten

6

Edukt 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 123083-Bromo-1-propanolHCID 676651,1'-(Bromomethylene)bis(4-fluorobenzene)

Produkt 1

HCID 14556323HCID 14556323, VerbindungAusbeute 68,8 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 36.9 g (0.130 mole) of bromobis(4-fluorophenyl)methane, 21.7 g (0.156 mole) of 3-bromopropanol, 16.6 g (0.156 mole) of sodium carbonate and a few potassium iodide crystals were heated to 130° C. for 16 hours. After cooling, the reaction mixture was diluted with water and extracted with ether. The ethereal phase was washed with water, dried on sodium sulfate and then concentrated to dryness. Distillation of the residue yielded 30.5 g (yield: 68%) of the desired propane.

Aufarbeitung

  1. temperatureAfter cooling
  2. extractionextracted with ether
  3. washThe ethereal phase was washed with water
  4. customdried on sodium sulfate
  5. concentrationconcentrated to dryness
  6. distillationDistillation of the residue

Quellen und Nachweise

ORD-Eintrag
ord-a0e664139cd24e3b8ea7721e27018984
Quelldatensatz
uspto-grants-1990_09
Patentnummer
US04957927

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