Lithium Hydroxide → HCID 15341834, Verbindung

HRID 1033652Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1033652
[NH2:1][C:2]([C:4]1[CH:30]=[CH:29][C:7]([O:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[C:14]([CH2:26][CH2:27][CH3:28])=[C:15]([CH:23]=[CH:24][CH:25]=2)[O:16][CH2:17][C:18]([O:20]CC)=[O:19])=[C:6]([CH2:31][CH:32]=[CH2:33])[C:5]=1[O:34][CH3:35])=[O:3].[OH-].[Li+]>CO>[NH2:1][C:2]([C:4]1[CH:30]=[CH:29][C:7]([O:8][CH2:9][CH2:10][CH2:11][O:12][C:13]2[C:14]([CH2:26][CH2:27][CH3:28])=[C:15]([CH:23]=[CH:24][CH:25]=2)[O:16][CH2:17][C:18]([OH:20])=[O:19])=[C:6]([CH2:31][CH:32]=[CH2:33])[C:5]=1[O:34][CH3:35])=[O:3]

Komponenten

4

Edukt 2

HCID 3939Lithium HydroxideHCID 15341833HCID 15341833, Verbindung

Produkt 1

HCID 15341834HCID 15341834, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

The compound of Example 55 (100 mg, 0.195 mmol) and 390 μl of 1M lithium hydroxide (0.3896 mmol) were added to 2.0 ml of methanol, and the reaction mixture was stirred at room temperature for 4 hours. The solvent was removed under vacuum, 5.0 ml of water was added to the residue, and the mixture was acidified with 10% hydrochloric acid. The mixture was filtered, and the white solid which was recovered was dried in a 40° C. oven overnight to give the product.

Aufarbeitung

  1. customThe solvent was removed under vacuum, 5.0 ml of water
  2. additionwas added to the residue
  3. filtrationThe mixture was filtered
  4. customthe white solid which was recovered
  5. customwas dried in a 40° C. oven overnight
  6. customto give the product

Quellen und Nachweise

ORD-Eintrag
ord-f3233f0e59ac4d499a7c557a339b6fd9
Quelldatensatz
uspto-grants-1994_05
Patentnummer
US05310951

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