Potassium Hydroxide → (S)-5-Methyl-3-nitromethyl-hexanoic acid dipotassium salt

HRID 1034570Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1034570
C([O:3][C:4](=[O:15])[CH2:5][C@@H:6]([CH2:11][N+:12]([O-:14])=[O:13])[CH2:7][CH:8]([CH3:10])[CH3:9])C.[OH-].[K+:17]>O>[K+:17].[K+:17].[CH3:9][CH:8]([CH3:10])[CH2:7][C@H:6]([CH2:11][N+:12]([O-:14])=[O:13])[CH2:5][C:4]([O-:15])=[O:3].[CH3:9][CH:8]([CH3:10])[CH2:7][C@H:6]([CH2:11][N+:12]([O-:14])=[O:13])[CH2:5][C:4]([O-:15])=[O:3]

Komponenten

4

Edukt 2

HCID 14797Potassium Hydroxide2×HCID 29984078(S)-5-methyl-3-nitromethyl-hexanoic acid ethyl ester

Produkt 1

HCID 131730882(S)-5-Methyl-3-nitromethyl-hexanoic acid dipotassium salt

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

830 mg of (S)-5-methyl-3-nitromethyl-hexanoic acid ethyl ester (VIII, R1=ethyl) were suspended in 0.8 mL of H2O. 900 mg of 50% aqueous KOH were added. After 5 h at 25° C. conversion was complete (determination by HPLC). The solvent was removed under reduced pressure to give a solid consisting of the title compound and minor amounts of KOH.

Aufarbeitung

  1. customThe solvent was removed under reduced pressure
  2. customto give a solid

Quellen und Nachweise

ORD-Eintrag
ord-7a302eaf53494bc18899a86728c391f3
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08546112B2

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