Oxalyl chloride → (Tetrahydro-2H-pyran-4-yl)acetyl chloride

HRID 1037842

Reaktionsgleichung

[O:1]1[CH2:6][CH2:5][CH:4]([CH2:7][C:8]([OH:10])=O)[CH2:3][CH2:2]1.C(Cl)(=O)C([Cl:14])=O>>[O:1]1[CH2:6][CH2:5][CH:4]([CH2:7][C:8]([Cl:14])=[O:10])[CH2:3][CH2:2]1

Komponenten

Edukt 2

HCID 65578Oxalyl chloride

HCID 2773575Tetrahydropyran-4-ylacetic acid

Produkt 1

HCID 24229747(Tetrahydro-2H-pyran-4-yl)acetyl chloride

Versuchsvorschrift

Commercially available (tetrahydro-pyran-4-yl)-acetic acid and oxalyl chloride were processed as described for example 9A to afford the title compound. MS (DCI/NH3) m/z 159 (M+H)+.

Quellen und Nachweise

ORD-Eintrag: ord-519e0b281e4242f7bc2346e0218a968f
Quelldatensatz: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08546583B2

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