Potassium Carbonate → (R,Z)-3-(2-{4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-(prop-1-en-1-yl)phenyl]-3-methylpiperazin-1-yl}-2-oxoethyl)-5-[4-(1-methylethoxy)phenyl]-5-methylimidazolidine-2,4-dione

Reaktionsgleichung

[CH3:1][CH:2]([O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2([CH3:18])[NH:15][C:14](=[O:16])[NH:13][C:12]2=[O:17])=[CH:7][CH:6]=1)[CH3:3].C(=O)([O-])[O-].[K+].[K+].Br[CH2:26][C:27]([N:29]1[CH2:34][CH2:33][N:32]([C:35]2[CH:40]=[CH:39][C:38]([C:41]([O:50]COC)([C:46]([F:49])([F:48])[F:47])[C:42]([F:45])([F:44])[F:43])=[CH:37][C:36]=2/[CH:54]=[CH:55]\[CH3:56])[C@H:31]([CH3:57])[CH2:30]1)=[O:28].Cl.C(OCC)(=O)C>CN(C)C=O.C(OCC)(=O)C.O>[F:48][C:46]([F:47])([F:49])[C:41]([C:38]1[CH:39]=[CH:40][C:35]([N:32]2[CH2:33][CH2:34][N:29]([C:27](=[O:28])[CH2:26][N:13]3[C:12](=[O:17])[C@:11]([C:8]4[CH:7]=[CH:6][C:5]([O:4][CH:2]([CH3:1])[CH3:3])=[CH:10][CH:9]=4)([CH3:18])[NH:15][C:14]3=[O:16])[CH2:30][CH:31]2[CH3:57])=[C:36](/[CH:54]=[CH:55]\[CH3:56])[CH:37]=1)([OH:50])[C:42]([F:45])([F:44])[F:43]