Acetic Anhydride → HCID 58938508, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[C:7]([C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:9])=[CH:6][N:5]=[CH:4][N:3]=1.[C:17](OC(=O)C)(=O)[CH3:18]>>[CH3:17][C:18]1[N:10]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:8](=[O:9])[C:7]2[C:2]([N:1]=1)=[N:3][CH:4]=[N:5][CH:6]=2Komponenten
3
Reaktionsbedingungen
- Temperatur
- 120 °C
Versuchsvorschrift
Compound 23 (70.0 mg, 0.32 mmol) was mixed with 6 mL of acetic anhydride and the reaction mixture was stirred at 120° C. for 2 h while monitored by MS. The reaction mixture was then concentrated in vacuo to yield 75 mg of crude compound 24 which was used for the next step without further purification.
Aufarbeitung
- concentrationThe reaction mixture was then concentrated in vacuo