HCID 178521700, Verbindung → HCID 178507186, Verbindung
Reaktionsgleichung
C(OC(=O)[NH:10][C:11]1([C:14]2[NH:18][N:17]=[N:16][N:15]=2)[CH2:13][CH2:12]1)C1C=CC=CC=1>CO.[Pd]>[NH:15]1[C:14]([C:11]2([NH2:10])[CH2:13][CH2:12]2)=[N:18][N:17]=[N:16]1Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
[1-(1H-tetrazol-5-yl)-cyclopropyl]-carbamic acid benzyl ester was dissolved in MeOH (5 ml). The solution was passed through a H-Cube hydrogenator at 0 bar, 30° C. and 1 ml/min with 10% Pd/C as a catalyst. The elute was concentrated to afford 48 mg of 1-(1H-tetrazol-5-yl)-cyclopropylamine as a solid product, m/z 126.5 [M+1]+.
Aufarbeitung
- concentrationThe elute was concentrated
Quellen und Nachweise
- ORD-Eintrag
- ord-1a589d74c5f941b19ed54273a8c12adf
- Quelldatensatz
- uspto-grants-2013_10
- Patentnummer
- US08552205B2
Notizen zur Reaktion
Wird geladen…