Homoserine lactone hydrobromide → 2-Amino-4-bromobutanoic acid hydrobromide

HRID 1040502

Reaktionsgleichung

Reaktionsgleichung von HRID 1040502
[BrH:1].[NH2:2][CH:3]1[CH2:8][CH2:7][O:6][C:4]1=[O:5]>Br.CC(O)=O>[BrH:1].[NH2:2][CH:3]([CH2:8][CH2:7][Br:1])[C:4]([OH:6])=[O:5]

Komponenten

4

Edukt 1

HCID 73508Homoserine lactone hydrobromide

Produkt 1

HCID 138779922-Amino-4-bromobutanoic acid hydrobromideAusbeute 64 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 176Acetic AcidLösungsmittelHCID 260Hydrogen BromideLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

A suspension of α-amino-γ-butyrolactone hydrobromide in 30% HBr in HOAc was heated at 100° C. in a sealed tube for 5 days. The mixture was concentrated to give a white solid that was washed with Et2O to provide 23.1 g (64%) of 2-amino-4-bromo-butyric acid hydrobromide.

Aufarbeitung

  1. concentrationThe mixture was concentrated
  2. customto give a white solid
  3. washthat was washed with Et2O

Quellen und Nachweise

ORD-Eintrag
ord-f38f179cf9dd4131a13e1590a509ceb1
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08552205B2

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