Hydrochloric Acid → 1-(Oxan-4-yl)piperazine--hydrogen chloride (1/2)

HRID 1043158Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1043158
[O:1]1[CH2:6][CH2:5][CH:4]([N:7]2[CH2:12][CH2:11][N:10](C(OC(C)(C)C)=O)[CH2:9][CH2:8]2)[CH2:3][CH2:2]1.[ClH:20]>CCOCC>[ClH:20].[ClH:20].[O:1]1[CH2:6][CH2:5][CH:4]([N:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH2:3][CH2:2]1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 46785855HCID 46785855, Verbindung

Produkt 1

HCID 441204811-(Oxan-4-yl)piperazine--hydrogen chloride (1/2)

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

To a solution of EXAMPLE 336A (3.92 g) in ether was added HCl (25 mL, 2M in ether) and the reaction mixture was stirred for 16 hours at room temperature. The solid product was filtered off, dried and used in next step without further purification.

Aufarbeitung

  1. filtrationThe solid product was filtered off
  2. customdried
  3. customused in next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-cc516472a3ad4afd8d54127785ca556d
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08557983B2

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