Nitric Acid → Citrulline Dinitrate

HRID 1046715Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1046715
[N+:1]([O-:4])([OH:3])=[O:2].[NH2:5][C@H:6]([C:14]([OH:16])=[O:15])[CH2:7][CH2:8][CH2:9][NH:10][C:11]([NH2:13])=[O:12].[N+:17]([O-:20])([OH:19])=[O:18].[NH2:21][C@H:22]([C:30]([OH:32])=[O:31])[CH2:23][CH2:24][CH2:25][NH:26][C:27]([NH2:29])=[O:28]>O>[N+:1]([O-:4])([OH:3])=[O:2].[N+:17]([O-:20])([OH:19])=[O:18].[NH2:5][C@H:6]([C:14]([OH:16])=[O:15])[CH2:7][CH2:8][CH2:9][NH:10][C:11]([NH2:13])=[O:12].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[NH2:21][C@H:22]([C:30]([OH:32])=[O:31])[CH2:23][CH2:24][CH2:25][NH:26][C:27]([NH2:29])=[O:28]

Komponenten

6

Edukt 3

HCID 944Nitric AcidHCID 9750CitrullineHCID 86628843Citrulline Nitrate

Produkt 2

HCID 86628841Citrulline DinitrateHCID 86628842Citrulline Trinitrate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Applicants have cost-effectively synthesized Citrulline Nitrate by combining nitric acid and Citrulline, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Citrulline Dinitrate or Citrulline Trinitrate. An alternative implementation may comprise using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Citrulline Nitrite. Citrulline Nitrite has the same effects as Citrulline Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Citrulline Nitrate-Orotate.

Aufarbeitung

  1. customleaving
  2. customto crystallize

Quellen und Nachweise

ORD-Eintrag
ord-ccefffc0915e48e9b0e6cce0a54cf6af
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08569369B2

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