Aminoacetaldehyde dimethyl acetal → HCID 178495885, Verbindung

HRID 1046991

Reaktionsgleichung

Reaktionsgleichung von HRID 1046991
[N:1]1[C:6]2[NH:7][C:8]3[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=3[C:10](=S)[NH:11][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH3:17][O:18][CH:19]([O:22][CH3:23])[CH2:20][NH2:21]>>[CH3:17][O:18][CH:19]([O:22][CH3:23])[CH2:20][NH:21][C:10]1[C:9]2[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=2[NH:7][C:6]2[N:1]=[CH:2][CH:3]=[CH:4][C:5]=2[N:11]=1

Komponenten

3

Edukt 2

HCID 89728Aminoacetaldehyde dimethyl acetalHCID 454962295,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-thione

Produkt 1

HCID 178495885HCID 178495885, Verbindung

Reaktionsbedingungen

Temperatur
95 °C

Versuchsvorschrift

A mixture of 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-thione (3.21 g, 14 mmol) and 2,2-dimethoxyethylamine (7.6 mL, 70 mmol) was heated to 95° C. for 1 hour. After cooling to room temperature the solvent was evaporated in vacuo. The crude product was used in the next step without further purification.

Aufarbeitung

  1. temperatureAfter cooling to room temperature the solvent
  2. customwas evaporated in vacuo
  3. customThe crude product was used in the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-1ddb5d730f7a48b5a2e2bc5cae496d22
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08569331B2

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