Acetone → Diallyl sulfone

HRID 1047508Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1047508
[CH2:1](O)[CH:2]=[CH2:3].O[O:6][S:7]([O-:9])=O.[K+].[CH3:11][C:12]([CH3:14])=O>O>[CH2:1]([S:7]([CH2:14][CH:12]=[CH2:11])(=[O:9])=[O:6])[CH:2]=[CH2:3]

Komponenten

5

Edukt 3

HCID 180AcetoneHCID 7858Allyl AlcoholHCID 23707502Potassium hydroxy sulfite

Produkt 1

HCID 159797Diallyl sulfoneAusbeute 72 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A solution of allyl alcohol isomer A from Step 2: (7.11 g, 16.65 mmol) and oxone (30.75 g, 50.0 mmol) in acetone (100 mL) and water (25 mL) was stirred at RT overnight then filtered, diluted with water and AcOEt, extracted with AcOEt, dried and concentrated. The residue is purified was purified by flash-chromatography over silica gel (eluted with Hexanes/AcOEt 99:1 to 60:40) to provide 5.50 g (72%) of allylsulfone.

Aufarbeitung

  1. filtrationthen filtered
  2. additiondiluted with water and AcOEt
  3. extractionextracted with AcOEt
  4. customdried
  5. concentrationconcentrated
  6. customThe residue is purified
  7. customwas purified by flash-chromatography over silica gel (eluted with Hexanes/AcOEt 99:1 to 60:40)

Quellen und Nachweise

ORD-Eintrag
ord-59046acae8df4ad0ba5efa000f86c0cf
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08569521B2

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