Water → HCID 22175090, Verbindung

HRID 1059656Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1059656
[O-:1][CH2:2][CH3:3].[Na+].F[C:6]1[CH:11]=[CH:10][N:9]=[CH:8][C:7]=1[O:12][CH2:13][O:14][CH2:15][CH2:16][Si:17]([CH3:20])([CH3:19])[CH3:18].O>C(O)C>[CH2:2]([O:1][C:6]1[CH:11]=[CH:10][N:9]=[CH:8][C:7]=1[O:12][CH2:13][O:14][CH2:15][CH2:16][Si:17]([CH3:20])([CH3:19])[CH3:18])[CH3:3]

Komponenten

5

Edukt 3

HCID 962WaterHCID 2723922Sodium ethoxideHCID 22175082HCID 22175082, Verbindung

Produkt 1

HCID 22175090HCID 22175090, VerbindungAusbeute 50,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

To a stirred solution of sodium ethoxide (0.9 g, 13 mmol) in ethanol (10 mL) was added all at once 10 (1.07 g, 4.4 mmol). The resulting mixture was stirred at room temperature for 48 hours, then poured into water (100 mL). The resulting mixture was extracted with ether (3×50 mL). The ether extracts were combined, dried (MgSO4) and concentrated. The resulting amber oil was chromatographed (silica gel, hexane-acetone, 4:1) to give 11 as a yellow oil (0.6 g).

Aufarbeitung

  1. extractionThe resulting mixture was extracted with ether (3×50 mL)
  2. dry with materialdried (MgSO4)
  3. concentrationconcentrated
  4. customThe resulting amber oil was chromatographed (silica gel, hexane-acetone, 4:1)

Quellen und Nachweise

ORD-Eintrag
ord-9bba8a0f8cfe460c9c449ea59c74940d
Quelldatensatz
uspto-grants-2003_02
Patentnummer
US06521622B1

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