Cyclopropylamine → HCID 86589545, Verbindung

Reaktionsgleichung

Cl[C:2]1[C:7]([C:8](OCC)=[S:9])=[CH:6][N:5]=[C:4]([CH3:13])[N:3]=1.[CH:14]1([NH2:17])[CH2:16][CH2:15]1>>[CH:14]1([NH:17][C:2]2[C:7]([CH:8]=[S:9])=[CH:6][N:5]=[C:4]([CH3:13])[N:3]=2)[CH2:16][CH2:15]1

Komponenten

Edukt 2

HCID 69828Cyclopropylamine

HCID 53249641Ethyl 4-chloro-2-methylthio-pyrimidine-5-carboxylate

Produkt 1

HCID 86589545HCID 86589545, Verbindung

Versuchsvorschrift

4-cyclopropylamino-2-methylthiopyrimidine-5-carboxaldehyde was prepared as described in Example 1 (steps A through C) starting with ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate (Aldrich Chemical Co.) and cyclopropyl amine (Aldrich Chemical Co.).

Quellen und Nachweise

ORD-Eintrag: ord-42d033f802eb4c85a30fd6a414b972f7
Quelldatensatz: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06965030B2

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