Morpholine → HCID 70550960, Verbindung

HRID 1065480Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1065480
[N+:1]([C:4]1[CH:19]=[CH:18][C:7]([CH:8]=[N:9][NH:10][C:11]2[N:12]=[N:13][C:14](Cl)=[CH:15][CH:16]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[NH:20]1[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1>CN(C)P(=O)(N(C)C)N(C)C>[N+:1]([C:4]1[CH:19]=[CH:18][C:7]([CH:8]=[N:9][NH:10][C:11]2[N:12]=[N:13][C:14]([N:20]3[CH2:25][CH2:24][O:23][CH2:22][CH2:21]3)=[CH:15][CH:16]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Komponenten

4

Edukt 2

HCID 8083MorpholineHCID 593142HCID 593142, Verbindung

Produkt 1

HCID 70550960HCID 70550960, VerbindungAusbeute 85,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 12679HexamethylphosphoramideLösungsmittel

Versuchsvorschrift

The mixture of 5.55 g (20 mmoles) of 4-nitrobenzylidene-(6-chloro-3-pyridazinyl)-hydrazine [prepared by the process described in Step a:], 7.66 g (88 mmoles) of morpholine and 5.5 ml of hexamethylphosphoric cid triamide is heated at 150° C. for 24 hours. After cooling, the mixture is triturated with 56 ml of water, the precipitate is filtered, washed with cold ethanol and dried to give 5.6 g (85%) of the named compound; m.p. 245° C. (with decomposition).

Aufarbeitung

  1. customprepared by the process
  2. temperatureAfter cooling
  3. customthe mixture is triturated with 56 ml of water
  4. filtrationthe precipitate is filtered
  5. washwashed with cold ethanol
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-50e66ff8481545c1857329f3e3d3d8fc
Quelldatensatz
uspto-grants-1982_05
Patentnummer
US04329457

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