Acetic Acid → [1-(p-Nitrophenyl)-1H-1,2,4-triazol-5-yl]pyrazine

Beteiligte Stoffe

Reaktionsschritte

A 10.0 g. portion of N-(dimethylaminomethylene)pyrazine carboxamide is added to a mixture of 10.3 g. of 4-nitrophenylhydrazine, 200 ml. of acetic acid and 50 ml. of p-dioxane. The mixture is heated at 90° for 5 hours and evaporated to dryness in vacuo. The residue is recrystallized from ethanol giving 9.0 g. of the desired product as tan crystals, mp. 188°-189° C.

Herkunft & Nachweise