Water → HCID 131712720, Verbindung

HRID 1065639Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1065639
[C:1]1([C:7]2[O:11][C:10](=[O:12])[NH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:13]([O:15][C:16]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][N:25]=[C:26]=[O:27])=[O:17])[CH3:14].O>CN(C=O)C>[CH2:13]([O:15][C:16]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][NH:25][C:26]([N:9]1[CH:8]=[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[O:11][C:10]1=[O:12])=[O:27])=[O:17])[CH3:14]

Komponenten

5

Edukt 3

HCID 962WaterHCID 123069965-Phenyloxazol-2-OLHCID 13991420HCID 13991420, Verbindung

Produkt 1

HCID 131712720HCID 131712720, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

16.1 g (0.1 mol) of 5-phenyl-4-oxazolin-2-one are dissolved in 100 ml of absolute DMF and 25.6 g (0.12 mol) of ethoxycarbonylheptyl isocyanate are added. The mixture is stirred for 24 hours at 50°-60° C., water is added and the oily/crystalline precipitate which is formed is separated, washed with water and dried in vacuo at room temperature. The crude product is recrystallised from ethanol.

Aufarbeitung

  1. customthe oily/crystalline precipitate which is formed
  2. customis separated
  3. washwashed with water
  4. customdried in vacuo at room temperature
  5. customThe crude product is recrystallised from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-02add52faab644d886d1a7657315e72b
Quelldatensatz
uspto-grants-1982_05
Patentnummer
US04330550

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