Hydrochloric Acid → S,S-Hexanediyldi-L-cysteine

HRID 1065749Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1065749
CS(O[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11]OS(C)(=O)=O)(=O)=O.Cl.[NH2:18][C@H:19]([C:22]([OH:24])=[O:23])[CH2:20][SH:21].[OH-:25].[Na+].Cl>O.C(O)C>[CH2:11]([S:21][CH2:20][C@@H:19]([C:22]([OH:23])=[O:25])[NH2:18])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][S:21][CH2:20][C@@H:19]([C:22]([OH:24])=[O:23])[NH2:18]

Komponenten

7

Edukt 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 60960Cysteine HydrochlorideHCID 1457351,6-Hexanediol, dimethanesulfonate

Produkt 1

HCID 53471696S,S-Hexanediyldi-L-cysteine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

At 70° C., under nitrogen, a mixture of 137 g of 1,6-hexanediyl dimethanesulfonate and 175.5 g of cysteine-hydrochloride monohydrated in 1.5 l of water containing a little ethanol is agitated. There is then slowly added a solution of 5 N NaOH so that the pH of the reaction mixture is maintained between 8.5 and 9.5. At the end of the reaction the mixture is acidified to pH 5.2 with a solution of HCl. The precipitate is filtered, washed thoroughly with water, then dried and analyzed.

Aufarbeitung

  1. temperatureis maintained between 8.5 and 9.5
  2. customAt the end of the reaction the mixture
  3. filtrationThe precipitate is filtered
  4. washwashed thoroughly with water
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-6a78a057348846899f816142eb81995d
Quelldatensatz
uspto-grants-1982_05
Patentnummer
US04331656

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