HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-[4-Methoxy-5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-pyrimidin-2-yl]-pyridine-2-carboxylic acid → 4-[4-Methoxy-5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-pyrimidin-2-yl]-pyridine-2-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-[4-Methoxy-5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-pyrimidin-2-yl]-pyridine-2-carboxylic acid | HCID 9892985 | — |
| Edukt | 1-Chloroethyl Cyclohexyl Carbonate | HCID 11229529 | — |
| Produkt | 4-[4-Methoxy-5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-pyrimidin-2-yl]-pyridine-2-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester | HCID 54399399 | — |
Reaktionsschritte
In analogy to example 77, from 4-[4-methoxy-5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-pyrimidin-2-yl]-pyridine-2-carboxylic acid, product of example 21, and cyclohexyl 1-chlorethyl carbonate (synthesis described by A. Riondel et al., Tetrahedron, 1988, Vol. 44, 1619) there was obtained 4-[4-methoxy-5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-pyrimidin-2-yl]-pyridine-2-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester as a white solid. ISN mass spectrum, m/e 692.1 (M−1 calculated for C33H35N5O10S: 692).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06242601B1 |
| Quelldatensatz | uspto-grants-2001_06 |
| ORD ID | ord-a0bf915339e2443c824931d35bba15b4 |
| Quellennotiz | uspto-grants-2001_06 |