Ammonia → Octyl 4'-hydroxy-4-biphenylcarboxylate

HRID 1066545

Reaktionsgleichung

Reaktionsgleichung von HRID 1066545
COC([O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[O:19])=[CH:14][CH:13]=2)=[CH:8][CH:7]=1)=O.N.ClCCl>C(O)C>[OH:5][C:6]1[CH:7]=[CH:8][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[O:19])=[CH:14][CH:13]=2)=[CH:10][CH:11]=1

Komponenten

5

Edukt 3

HCID 222AmmoniaHCID 6344DichloromethaneHCID 18328376Octyl4'-methoxycarbonyloxy-4-biphenylcarboxylate

Produkt 1

HCID 14692993Octyl 4'-hydroxy-4-biphenylcarboxylate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of compound 5 (5.25 g, 0.014 mol) and aqueous ammonia (35% w/v, 100 ml) in ethanol (200 ml) was stirred for 1 h at room temperature. TLC analysis (dichloromethane) revealed a complete reaction. The solvent was removed in vacuo and the shite solid was recrystallised from ethanol to give colourless crystals.

Aufarbeitung

  1. customa complete reaction
  2. customThe solvent was removed in vacuo
  3. customthe shite solid was recrystallised from ethanol
  4. customto give colourless crystals

Quellen und Nachweise

ORD-Eintrag
ord-4c0928ed998b44f0abc8a9f40a5bde1b
Quelldatensatz
uspto-grants-2001_06
Patentnummer
US06242636B1

Verknüpfte Notizen

Wird geladen…