3-Ethoxy-4-nitrobenzoic acid → 4-Amino-3-ethoxybenzoic acid

HRID 1070932

Reaktionsgleichung

Reaktionsgleichung von HRID 1070932
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[N+:13]([O-])=O)[C:7]([OH:9])=[O:8])[CH3:2]>[Pd]>[NH2:13][C:12]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][C:4]=1[O:3][CH2:1][CH3:2]

Komponenten

3

Edukt 1

HCID 223975093-Ethoxy-4-nitrobenzoic acid

Produkt 1

HCID 223974484-Amino-3-ethoxybenzoic acidAusbeute 92,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

3-Ethoxy-4-nitrobenzoic acid (0.31 g) was treated with 5% palladium on charcoal under an atmosphere of hydrogen (1 bar) for 3 hours. The reaction mixture was filtered and the filtrate was evaporated to leave the product as a beige solid (0.245 g; MS: ES−(M−H) 180).

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-fb2bc67d654c4bbf90293a193e4e96cc
Quelldatensatz
uspto-grants-2005_06
Patentnummer
US06903115B2

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