3-Aminopyrrolidine → HCID 18640048, Verbindung

HRID 1073311Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1073311
[Cl-:1].[K+].[Pt+2:3].[Cl-:4].[Cl-].[NH2:6][CH:7]1[CH2:11][CH2:10][NH:9][CH2:8]1>O>[Pt+2:3].[Cl:1][C@H:8]1[C@@H:7]([NH2:6])[CH2:11][CH2:10][N:9]1[Cl:4]

Komponenten

4

Edukt 2

HCID 1644013-AminopyrrolidineHCID 86744074platinum (II) potassium chloride

Produkt 1

HCID 18640048HCID 18640048, VerbindungAusbeute 67,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To a solution of platinum (II) potassium chloride (12.2 g) in water (800 ml) is added (3RS)-3-aminopyrrolidine (2.5 g), and the mixture is stirred at room temperature for 19 hours. The precipitated solid is removed by filtration, and the filtrate is concentrated under reduced pressure. To the residue is added a small amount of water, and the resulting crystals are separated by filtration and washed with water and acetone to give cis-dichloro-(3RS)-3-aminopyrrolidine platinum (II) (6.9 g) as pale yellow crystal.

Aufarbeitung

  1. customThe precipitated solid is removed by filtration
  2. concentrationthe filtrate is concentrated under reduced pressure
  3. additionTo the residue is added a small amount of water
  4. customthe resulting crystals are separated by filtration
  5. washwashed with water and acetone

Quellen und Nachweise

ORD-Eintrag
ord-d31b2055efa54c618585d4f5e5009d7a
Quelldatensatz
uspto-grants-1990_11
Patentnummer
US04968800

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