Methanol → (3-Chloropropyl)octadecyldimethylammonium bromide

HRID 1075405

Reaktionsgleichung

[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH3:3].[Br:22][CH2:23][CH2:24][CH2:25][Cl:26].CO>CC(CC)=O>[Br-:22].[Cl:26][CH2:25][CH2:24][CH2:23][N+:2]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])([CH3:1])[CH3:3]

Komponenten

Reaktionsbedingungen

Temperatur: 65 °C

Versuchsvorschrift

A 1000 mL, round-bottomed flask equipped with air condensers and a magnetic stirring plate was charged with N,N-dimethyloctadecylamine (301.0 grams, 1.01 moles), 1-bromo-3-chloropropane (1700 grams, 1.08 moles) and methanol (200 mL). The reaction was maintained at 65° C. for 18 hours. Solvent was removed by rotary evaporation under reduced pressure to yield clear oil. The oil was transferred to a beaker containing methylethylketone (250 mL) causing a white precipitate to form. Solid material was collected by vacuum filtration, resuspended in methylethylketone (250 mL) and collected by vacuum filtration an additional two times. The solid was placed in a vacuum oven at 30° C. overnight. Yield 274.9 grams (0.59 moles, 58%).

Aufarbeitung

customA 1000 mL, round-bottomed flask equipped with air condensers
customSolvent was removed by rotary evaporation under reduced pressure
customto yield clear oil
customto form
filtrationSolid material was collected by vacuum filtration
filtrationcollected by vacuum filtration an additional two times

Quellen und Nachweise

ORD-Eintrag: ord-e0bd1728d4704a6d8a1cf97aa5c12e2b
Quelldatensatz: uspto-grants-1999_05
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05900475

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