Ethanol → HCID 86754078, Verbindung

HRID 1075699Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1075699
C([NH:4][CH2:5][CH2:6][O:7][CH2:8][C:9]([O-:11])=[O:10])(=O)C.[Na+:12].[OH-].[Na+].CCO>O>[NH2:4][CH2:5][CH2:6][O:7][CH2:8][C:9]([O-:11])=[O:10].[Na+:12]

Komponenten

5

Edukt 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 86754077HCID 86754077, Verbindung

Produkt 1

HCID 86754078HCID 86754078, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

52 g of sodium 5-acetylamino-3-oxapentanoate were dissolved in 200 ml of water. 11.4 g of NaOH were added at 20° C., and the reaction mixture was then heated at 100° C. for 8 h until precursor was no longer detectable. Then 200 ml of EtOH were added and the pH was adjusted to about 6, resulting in pure crystals of sodium 5-amino-3-oxapentanoate. The crude product resulting after removal of the solvent by distillation as a mixture with sodium acetate weighing 63.3 g (corresponding to 100% of theory) could be employed without prior precipitation for the subsequent reaction.

Quellen und Nachweise

ORD-Eintrag
ord-73112dd8f6c24967aaee3dc92f68f0da
Quelldatensatz
uspto-grants-1999_05
Patentnummer
US05907055

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