3-Cyclopentylpropionyl chloride → 13beta-Ethyl-17beta-(3-cyclopentylpropionoxy)-gon-4-en-3-one

Beteiligte Stoffe

Reaktionsschritte

Add 3-cyclopentylpropionyl chloride (2 g.) in benzene (6 cc.) to 13β-ethyl-17β-hydroxy-gon-4-en-3-one (2 g.) in pyridine (6 cc.) at -15°. Keep the mixture at -10° for 17 hours, work up and recrystallize the product from methanol to give the title compound, m.p. 88-89°; ultraviolet absorption peak at 241 mμ (ε17,000); infrared absorption peaks at 5.80; 6.00, 6.18 μ.

Herkunft & Nachweise