huagongshe.com
HRID1077194

反应详情

EQUATION

反应方程式

HRID 1077194 的结构方程式

REACTANTS

反应物

2
结构：O=C(Cl)CCC1CCCC1
HCID66039

3-Cyclopentylpropionyl chloride

C8H13ClO

结构：CC[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@H]43)[C@@H]1CC[C@@H]2O
HCID10039774

Gon-4-en-3-one, 13-ethyl-17-hydroxy-, (17β)-(±)-

C19H28O2

PRODUCTS

生成物

1
结构：CC[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@H]43)[C@@H]1CC[C@@H]2OC(=O)CCC1CCCC1
HCID22790393

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：c1ccccc1
溶剂HCID241

Benzene

C6H6

结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

Add 3-cyclopentylpropionyl chloride (2 g.) in benzene (6 cc.) to 13β-ethyl-17β-hydroxy-gon-4-en-3-one (2 g.) in pyridine (6 cc.) at -15°. Keep the mixture at -10° for 17 hours, work up and recrystallize the product from methanol to give the title compound, m.p. 88-89°; ultraviolet absorption peak at 241 mμ (ε17,000); infrared absorption peaks at 5.80; 6.00, 6.18 μ.

WORKUP

后处理

  1. customat -10°
  2. customfor 17 hours
  3. customrecrystallize the product from methanol