HCID 10704523, Verbindung → 1-(4-Trifluoromethylphenyl)imidazolidin-2-one

HRID 1077899Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1077899
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH:13]=[CH:12][NH:11][C:10]2=[O:14])=[CH:5][CH:4]=1>C(O)(=O)C.[C].[Pd]>[F:16][C:2]([F:1])([F:15])[C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:13][CH2:12][NH:11][C:10]2=[O:14])=[CH:7][CH:8]=1

Komponenten

4

Edukt 1

HCID 10704523HCID 10704523, Verbindung

Produkt 1

HCID 106809511-(4-Trifluoromethylphenyl)imidazolidin-2-oneAusbeute 81,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

1-(4-Trifluoromethylphenyl)-2(1H,3H)-imidazolone (1.15 g) was dissolved in 20 ml of acetic acid. 10% Palladium-carbon (0.3 g) was added thereto and the mixture was stirred under a hydrogen stream for six hours. The catalyst was filtered off, the solvent was distilled off and the residue was recrystallized from ethyl acetate-diisopropyl ether to give 0.95 g of 1-(4-trifluoromethylphenyl)-2-imidazolidinone as colorless prisms.

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. distillationthe solvent was distilled off
  3. customthe residue was recrystallized from ethyl acetate-diisopropyl ether

Quellen und Nachweise

ORD-Eintrag
ord-bfb5d0481829473cb2ea3ef28bac0159
Quelldatensatz
uspto-grants-1996_08
Patentnummer
US05545652

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