Triethylamine → HCID 14719431, Verbindung

HRID 1085375

Reaktionsgleichung

Reaktionsgleichung von HRID 1085375
[CH2:1]([O:19][CH2:20][CH2:21][CH2:22][OH:23])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:24][S:25](Cl)(=[O:27])=[O:26].C(N(CC)CC)C>ClCCl>[CH3:24][S:25]([O:23][CH2:22][CH2:21][CH2:20][O:19][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])(=[O:27])=[O:26]

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 5553033-Octadecyloxypropanol

Produkt 1

HCID 14719431HCID 14719431, VerbindungAusbeute 98 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

In dichloromethane (50 ml) is dissolved 3-(octadecyloxy)propanol (8.0 g). To the solution are added, under ice-cooling, methanesulfonyl chloride (4.18 g) and triethylamine (5.1 ml). The mixture is stirred at room temperature for one hour. The reaction mixture is washed with water and an aqueous solution of sodium hydrogencarbonate, successively, and then dried. The solvent is distilled off under reduced pressure to give the above-titled compound (9.7 g).

Aufarbeitung

  1. additionTo the solution are added, under ice-
  2. temperaturecooling
  3. washThe reaction mixture is washed with water
  4. dry with materialan aqueous solution of sodium hydrogencarbonate, successively, and then dried
  5. distillationThe solvent is distilled off under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5231a62ac23d4fbd8898c56889ce6997
Quelldatensatz
uspto-grants-1991_04
Patentnummer
US05008454

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