Hydrazine hydrate (1:1) → HCID 20060099, Verbindung

HRID 1085465Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1085465
Cl[C:2]1[N:7]=[C:6]([CH3:8])[CH:5]=[C:4]([CH:9]2[CH2:11][CH2:10]2)[N:3]=1.O.[NH2:13][NH2:14]>C(O)C>[NH:13]([C:2]1[N:7]=[C:6]([CH3:8])[CH:5]=[C:4]([CH:9]2[CH2:11][CH2:10]2)[N:3]=1)[NH2:14]

Komponenten

4

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 19804698HCID 19804698, Verbindung

Produkt 1

HCID 20060099HCID 20060099, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

3.0 g of 2-chloro-4-methyl-6-cyclopropylpyrimidine are dissolved in 30 ml of ethanol; 3.8 ml of hydrazine hydrate are added and the mixture is stirred for 20 hours at room temperature. The solvent is then evaporated off in vacuo and the residue is recrystallised with ethyl acetate. M.p. 98°-99° C.

Aufarbeitung

  1. customThe solvent is then evaporated off in vacuo
  2. customthe residue is recrystallised with ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-80d05987f4c04b3f87a30da479f6ac04
Quelldatensatz
uspto-grants-1991_04
Patentnummer
US05010082

Notizen zur Reaktion

Wird geladen…