Morpholine → (5R,6S)-3-[2-{(2S)-4-fluoropyrrolidin-2-yl}-1-methylethenyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Reaktionsgleichung

C(OC([N:7]1[CH2:11][CH:10]([F:12])[CH2:9][C@H:8]1[CH:13]=[C:14]([C:16]1[CH2:22][C@H:21]2[N:18]([C:19](=[O:26])[C@@H:20]2[C@H:23]([OH:25])[CH3:24])[C:17]=1[C:27]([O:29]CC=C)=[O:28])[CH3:15])=O)C=C.N1CCOCC1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>O1CCCC1.C(O)C.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[F:12][CH:10]1[CH2:11][NH:7][C@H:8]([CH:13]=[C:14]([C:16]2[CH2:22][C@H:21]3[N:18]([C:19](=[O:26])[C@@H:20]3[C@H:23]([OH:25])[CH3:24])[C:17]=2[C:27]([OH:29])=[O:28])[CH3:15])[CH2:9]1