Water → 1,2-Benzenediamine,N1-(3-phenyl-2-propen-1-yl)-

HRID 1090582

Reaktionsgleichung

Reaktionsgleichung von HRID 1090582
[C:1]1([NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH2:7].C(=O)([O-])[O-].[K+].[K+].[CH2:15](Cl)[CH:16]=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.O>CN(C)C=O>[CH2:15]([NH:7][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=1[NH2:8])[CH:16]=[CH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Komponenten

6

Edukt 4

HCID 962WaterHCID 7243O-PhenylenediamineHCID 11430Potassium CarbonateHCID 94242Benzene, (3-chloro-1-propenyl)-

Produkt 1

HCID 27716631,2-Benzenediamine,N1-(3-phenyl-2-propen-1-yl)-Ausbeute 89,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

3.24 g of ortho-phenylenediamine was dissolved in 30 ml of dimethylformamide, to the solution were added 2.07 g of potassium carbonate and 1.52 g of cinnamyl chloride, and the mixture was stirred overnight at a room temperature. After adding 100 ml of water, the reaction mixture was extracted twice with 100 ml and 50 ml of chloroform, and the extract was washed with a saturated sodium chloride aqueous solution, dried over magnesium sulfate and evaporated to remove the solvent under a reduced pressure. The resulting residue was applied to a silica gel column and eluted with chloroform, to obtain 2.0 g of the title compound as light brown crystals.

Aufarbeitung

  1. extractionthe reaction mixture was extracted twice with 100 ml and 50 ml of chloroform
  2. washthe extract was washed with a saturated sodium chloride aqueous solution
  3. dry with materialdried over magnesium sulfate
  4. customevaporated
  5. customto remove the solvent under a reduced pressure
  6. washeluted with chloroform

Quellen und Nachweise

ORD-Eintrag
ord-a7e0d5e171c84e88ae43b3ef41f02629
Quelldatensatz
uspto-grants-1992_01
Patentnummer
US05081246

Verknüpfte Notizen

Wird geladen…