Bromine → 1-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

HRID 1093015Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1093015
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH2:11][C:12](=[O:14])[CH3:13])[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3].[Br:15]Br>O1CCOCC1>[Br:15][CH:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([S:2]([CH3:1])(=[O:3])=[O:4])[CH:6]=1)[C:12](=[O:14])[CH3:13]

Komponenten

4

Edukt 2

HCID 24408BromineHCID 665884811-(3-(Methylsulfonyl)phenyl)propan-2-one

Produkt 1

HCID 858616531-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

A stirred solution of 1-(3-methanesulphonyl-phenyl)-propan-2-one (176b) (0.25 g, 1.18 mmol) in dioxane (10 ml) at 5° C. is treated with bromine (0.131 g, 0.82 mmol) added in two portions. The reaction is stirred and allowed to warm up to room temperature. The solvent is removed in vacuo to yield an orange oil of the titled compound.

Aufarbeitung

  1. additionadded in two portions
  2. customThe solvent is removed in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-7322d988ca48436db43a24f062528d8b
Quelldatensatz
uspto-grants-2012_03
Patentnummer
US08129541B2

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