HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ammonia → 5-iodo-6-methyl-1H-indazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ammonia | HCID 222 | — |
| Edukt | 1-Acetyl-5-iodo-6-methylindazole | HCID 59339735 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 5-iodo-6-methyl-1H-indazole | HCID 59339696 | 100,8% |
Reaktionsschritte
1-Acetyl-5-iodo-6-methylindazole (1.5 g, 5.0 mmol) was stirred with ammonia (7 M in methanol, 4 mL) in methano/THF (2/1, 15 mL) for 1 h. The solution was evaporated to give the subtitle compound (1.3 g, 100%) as an off-white powder.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08143290B2 |
| Quelldatensatz | uspto-grants-2012_03 |
| ORD ID | ord-e5f1e91d0e524ac58251a831aedaba9c |
| Quellennotiz | uspto-grants-2012_03 |