[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde → 6-Phenyl-1,2,4-triazin-3(2H)-one

HRID 1099030Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1099030
[NH2:1][C:2]([NH:4][N:5]=[C:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH:7]=O)=[O:3]>C(O)(=O)C>[C:9]1([C:6]2[CH:7]=[N:1][C:2](=[O:3])[NH:4][N:5]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Komponenten

3

Edukt 1

HCID 54444391[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde

Produkt 1

HCID 112637836-Phenyl-1,2,4-triazin-3(2H)-oneAusbeute 90,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde (3.00 g, 0.0157 mol) in acetic acid (15.0 mL) was heated at 130° C. for 6 h. After cooling, the solvent was removed under reduced pressure. The residue was triturated with ether, filtered, washed with ether, and dried under high vacuum to give the desired product (2.45 g, 90.1%). Analytical LCMS: (M+H)+=174.0.

Aufarbeitung

  1. temperatureAfter cooling
  2. customthe solvent was removed under reduced pressure
  3. customThe residue was triturated with ether
  4. filtrationfiltered
  5. washwashed with ether
  6. customdried under high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-7df081a83a6040e1878edd9837546375
Quelldatensatz
uspto-grants-2012_03
Patentnummer
US08143251B2

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