3-(Nitro-n-butylamino)benzophenone → HCID 54315355, Verbindung

HRID 1105839Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1105839
[N+]([N:4](CCCC)[C:5]1[CH:6]=[C:7]([CH:16]=[CH:17][CH:18]=1)[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:9])([O-])=O.[H][H]>C(O)C.[Pd]>[NH2:4][C:5]1[CH:6]=[C:7]([CH:16]=[CH:17][C:18]=1[NH:4][CH2:5][CH2:18][CH2:17][CH3:16])[C:8]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[O:9]

Komponenten

5

Edukt 2

HCID 205552293-(Nitro-n-butylamino)benzophenoneHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 54315355HCID 54315355, VerbindungAusbeute 88,6 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of 3-(nitro-4-n-butylamino)-benzophenone (5.96 g.; 0.02 mole) in ethanol (200 ml.) is added palladium on charcoal (5%; 0.1 g.). The mixture is hydrogenated until theoretical uptake of hydrogen has occurred (about three hours) and then let stand at room temperature overnight. The reaction mixture is filtered to remove the catalyst and the filtrate concentrated under vacuum to afford 4.75 g. (88.6% yield) of 3-amino-4-n-butylaminobenzophenone.

Aufarbeitung

  1. custom(about three hours)
  2. filtrationThe reaction mixture is filtered
  3. customto remove the catalyst
  4. concentrationthe filtrate concentrated under vacuum
  5. customto afford 4.75 g

Quellen und Nachweise

ORD-Eintrag
ord-36486451a3814c69a32801938eb84ea6
Quelldatensatz
uspto-grants-1982_01
Patentnummer
US04310537

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