HCID 21253084, Verbindung → HCID 21253068, Verbindung

HRID 1106437Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1106437
[ClH:1].[Br:2][C:3]1[CH:12]=[C:11]([N+:13]([O-])=O)[C:10]([NH2:16])=[C:9]2[C:4]=1[CH2:5][CH2:6][NH:7][CH2:8]2>CO.[Pd]>[ClH:1].[BrH:2].[CH2:8]1[C:9]2[C:4](=[CH:3][CH:12]=[C:11]([NH2:13])[C:10]=2[NH2:16])[CH2:5][CH2:6][NH:7]1

Komponenten

4

Edukt 1

HCID 21253084HCID 21253084, Verbindung

Produkt 1

HCID 21253068HCID 21253068, VerbindungAusbeute 99 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

The product from Example 5 (7 g) in 250 mL of methanol was treated with 20% Pd/C (1 g) and shaken on a Parr apparatus under a hydrogen atmosphere (50 psi) for 16 h at ambient temperature. The catalyst was removed by filtration and the filtrate evaporated to give the product as a purple solid (6.3 g, 99% yield) that was used immediately without further purification.

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. customthe filtrate evaporated

Quellen und Nachweise

ORD-Eintrag
ord-9fb7d984c45b417eb7069af3b7ee1949
Quelldatensatz
uspto-grants-2000_05
Patentnummer
US06057313

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