Hexadecylamine → N-(2-hydroxyethoxy)ethyl-n-hexadecylamine

HRID 1107605

Reaktionsgleichung

Reaktionsgleichung von HRID 1107605
[CH2:1]([NH2:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].Cl[CH2:19][CH2:20][O:21][CH2:22][CH2:23][OH:24].[OH-].[K+].C(O)C>C(O)C>[OH:24][CH2:23][CH2:22][O:21][CH2:20][CH2:19][NH:17][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Komponenten

5

Edukt 3

HCID 8926HexadecylamineHCID 123612-(Chloroethoxy)ethanolHCID 21946426Potassium hydroxide ethanol

Produkt 1

HCID 9996690N-(2-hydroxyethoxy)ethyl-n-hexadecylamineAusbeute 70 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Into a 1 l rounded-flask, were introduced 48.2 g of hexadecyl amine and 700 ml of ethanol. The mixture was heated to reflux, and then was gradually added 11 ml of 2-(2-chloroethoxy)ethanol. The mixture was refluxed for 3 hours and cooled to a room temperature. Thereto was added solution of KOH/ethanol to produce precipitates, which were removed by filtration. The filtrate was concentrated under reduced pressure, and then was recrystallized from ethanol, and dried to give 24.1 g of the title compound(Yield: 70%) as white powder, which was identified by IR and NMR. The results are shown in Table 1.

Aufarbeitung

  1. temperatureThe mixture was heated
  2. temperatureto reflux
  3. temperatureThe mixture was refluxed for 3 hours
  4. customto produce
  5. customprecipitates
  6. customwhich were removed by filtration
  7. concentrationThe filtrate was concentrated under reduced pressure
  8. customwas recrystallized from ethanol
  9. customdried

Quellen und Nachweise

ORD-Eintrag
ord-7b93908ad6e64715811b802693a3f15e
Quelldatensatz
uspto-grants-2000_05
Patentnummer
US06060612

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