Formamide → Ethyl 4-methyloxazole-5-carboxylate

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To ethyl-2-chloroacetoacetate(5.6 g) was added formamide(4.6 g). The reaction mixture was stirred at 120° C. for 12 hours, cooled to 0° C. and aqueous potassium carbonate was added thereto. The mixture was extracted with benzene, dried with anhydrous magnesium sulfate, and concentrated in vacuo to obtain the target product(2.1 g).

Herkunft & Nachweise