Formaldehyde → Dimethyl alpha-hydroxymethyl-alpha-fluoromalonate

HRID 1109276

Reaktionsgleichung

Reaktionsgleichung von HRID 1109276
[F:1][CH:2]([C:7]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4].[CH2:11]=[O:12]>>[OH:12][CH2:11][C:2]([F:1])([C:7]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4]

Komponenten

3

Versuchsvorschrift

The process according to the invention for preparing an α-fluoroacrylic acid ester is carried out in three stages. First dimethyl α-fluoromalonate is reacted with formaldehyde to give dimethyl a-hydroxymethyl-α-fluoromalonate, which is then hydrolyzed and the hydrolysis product is dicarboxylated and dehydrated, and finally the resulting α-fluoroacrylic acid is esterified with an alcohol of the formula (3).

Quellen und Nachweise

ORD-Eintrag
ord-fca26e6d78084861ac2ddc1bf309c09d
Quelldatensatz
uspto-grants-1994_06
Patentnummer
US05319131

Verknüpfte Notizen

Wird geladen…