3-Nitro-5-(octadecyloxy)benzoic acid methyl ester → 3-Amino-5-(octadecyloxy)benzoic acid methyl ester

HRID 1110258Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1110258
[CH3:1][O:2][C:3](=[O:32])[C:4]1[CH:9]=[C:8]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:7]=[C:6]([N+:29]([O-])=O)[CH:5]=1>[Pd].C1COCC1>[CH3:1][O:2][C:3](=[O:32])[C:4]1[CH:9]=[C:8]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:7]=[C:6]([NH2:29])[CH:5]=1

Komponenten

4

Edukt 1

HCID 536989543-Nitro-5-(octadecyloxy)benzoic acid methyl ester

Produkt 1

HCID 193890883-Amino-5-(octadecyloxy)benzoic acid methyl esterAusbeute 99 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

A mixture of 3.55 g of 3-nitro-5-(octadecyloxy)benzoic acid methyl ester and 0.75 g of 10% palladium on carbon in 100 ml of THF was shaken under an initial hydrogen pressure of 52 psi until uptake ceased after 1.5 hours. The catalyst was removed by filtration and the filtrate was concentrated at reduced pressure to give 3.28 g of pure 3-amino-5-(octadecyloxy)benzoic acid methyl ester.

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated at reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-442c2d56145e401fb9be993122ddb862
Quelldatensatz
uspto-grants-1994_06
Patentnummer
US05324747

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