Ammonium → tert-butyl benzyl(4-((5-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)(hydroxy)methyl)bicyclo[2.2.2]octan-1-yl)carbamate
Reaktionsgleichung
[CH2:27]([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[N:34]([C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[C:42]12[CH2:43][CH2:44][C:45]([CH:50]=[O:51])([CH2:46][CH2:47]1)[CH2:48][CH2:49]2.[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:22][CH2:23][CH2:24][CH2:25][Li:26].[CH3:59][CH2:60][O:61][C:62]([CH3:63])=[O:64].[Cl-:52].[Cl:1][c:2]1[c:3]([I:21])[c:4]2[c:5]([n:6][cH:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2.[NH4+:53]>>[Cl:1][c:2]1[c:3]([CH:50]([C:45]23[CH2:44][CH2:43][C:42]([N:34]([CH2:27][c:28]4[cH:29][cH:30][cH:31][cH:32][cH:33]4)[C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])([CH2:47][CH2:46]2)[CH2:49][CH2:48]3)[OH:51])[c:4]2[c:5]([n:6][cH:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2
