Potassium Carbonate → 2-(1,4-BENZODIOXAN-2YL)-METHYLENE-BENZIMIDAZOLE

HRID 1155294Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1155294
Cl.[O:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[O:5][CH2:4][CH:3]1[CH2:12][C:13]1[NH:14][C:15]2[CH:21]=[CH:20][CH:19]=[CH:18][C:16]=2[N:17]=1.C(=O)([O-])[O-].[K+].[K+]>CCOCC>[O:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[O:5][CH2:4][CH:3]1[CH2:12][C:13]1[NH:17][C:16]2[CH:18]=[CH:19][CH:20]=[CH:21][C:15]=2[N:14]=1

Komponenten

4

Edukt 2

HCID 11430Potassium CarbonateHCID 12761781HCID 12761781, Verbindung

Produkt 1

HCID 127617802-(1,4-BENZODIOXAN-2YL)-METHYLENE-BENZIMIDAZOLE

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

2-(1,4-benzodioxan-2-ylmethyl)benzimidazole hydrochloride (1.0 g) suspended in 50 ml of ether is stirred with excess dilute aqueous potassium carbonate solution until the salt is completely dissolved. The organic layer is then separated, washed twice with water, dried over magnesium sulfate and evaporated to yield 2-(1,4-benzodioxan-2-ylmethyl)benzimidazole.

Aufarbeitung

  1. dissolutionis completely dissolved
  2. customThe organic layer is then separated
  3. washwashed twice with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-54f10b772d3b4f11b68bee647f30b9b3
Quelldatensatz
uspto-grants-1981_11
Patentnummer
US04301171

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