Triethylamine → p-BROMOPHENYL 1-(p-CHLOROPHENYLSULFONYL)VINYL SULFIDE

HRID 1156385Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1156385
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH:9]([S:12]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)(=[O:14])=[O:13])[CH2:10]Cl)=[CH:4][CH:3]=1.C(N(CC)CC)C>O1CCCC1.C(OCC)C>[Cl:21][C:18]1[CH:17]=[CH:16][C:15]([S:12]([C:9]([S:8][C:5]2[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=2)=[CH2:10])(=[O:14])=[O:13])=[CH:20][CH:19]=1

Komponenten

5

Edukt 2

HCID 8471TriethylamineHCID 130448002-CHLORO-1-(p-CHLOROPHENYLSULFONYL)ETHYL p-BROMOPHENYL SULFIDE

Produkt 1

HCID 13044811p-BROMOPHENYL 1-(p-CHLOROPHENYLSULFONYL)VINYL SULFIDEAusbeute 40,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

Thirty-five grams (82 mmoles) of 2-chloro-1-(p-chlorophenylsulfonyl)ethyl p-bromophenyl sulfide was dissolved in 100 ml of tetrahydrofuran and treated with 12 ml (86 mmoles) of triethylamine. The mixture was diluted with 100 ml of diethyl ether and allowed to stand for 15 minutes. The precipitated triethylamine hydrochloride was separated by filtration. Evaporation of solvent from the filtrate gave 35 g of crude solid m.p. 45°-95°. Recrystallization from 100 ml of ethyl acetate-pentane (45:55) gave 13 g of pure product, m.p. 97°-99°.

Aufarbeitung

  1. customThe precipitated triethylamine hydrochloride was separated by filtration
  2. customEvaporation of solvent from the filtrate
  3. customgave 35 g of crude solid m.p. 45°-95°
  4. customRecrystallization from 100 ml of ethyl acetate-pentane (45:55)

Quellen und Nachweise

ORD-Eintrag
ord-eb4557c5d75a4e4ab7e7818c24cc9fc8
Quelldatensatz
uspto-grants-1982_06
Patentnummer
US04335142

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