4-(2-(4-Methyl-3-nitrophenoxy)ethyl)morpholine → 2-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline

HRID 1158082Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1158082
[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:4][C:3]=1[N+:17]([O-])=O>CO.[Pd]>[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:4][C:3]=1[NH2:17]

Komponenten

4

Edukt 1

HCID 589298674-(2-(4-Methyl-3-nitrophenoxy)ethyl)morpholine

Produkt 1

HCID 393350392-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To the mixture of 4-(2-(4-methyl-3-nitrophenoxy)ethyl)morpholine (532 mg, 2 mmol) in MeOH (50 mL) was added 10% Pd/C (250 mg). The mixture was stirred under an atmosphere of H2 (balloon) overnight. The contents of the reaction mixture were then filtered and concentrated in vacuo to give the title product, which was used without further purification.

Aufarbeitung

  1. filtrationThe contents of the reaction mixture were then filtered
  2. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-808f4509d16948bc8ff9b78cf976924c
Quelldatensatz
uspto-grants-2010_10
Patentnummer
US07807700B2

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